2021 2^nd International Conference on Information Science, Parallel and Distributed Systems （ISPDS 2021）will provide an excellent international forum for sharing knowledge and results in theory, methodology and applications of Information Science, Parallel and Distributed Computing. Original papers are invited on Information technology, Algorithms and Applications, Computer Networks, Cyber trust and security, Wireless networks and mobile computing and Bioinformatics. The aim of the conference is to provide a platform to the researchers and practitioners from both academia as well as industry to meet and share cutting-edge development in the field. Authors are solicited to contribute to the conference by submitting articles that illustrate research results, projects, surveying works and industrial experiences that describe significant advances in the related areas.